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Ased severity and risk of respiratory syncytial virus infection [186]. Tobacco smoke contains more than 4000 chemical, 250 of which are known to be harmful and 50 carcinogenic. The main constituents of tobacco smoke that harm the respiratory apparatus include carbon monoxide, nitrogen oxide, formaldehyde, hydrogen cyanide, sulphur dioxide, nitrosamines, nicotine, heavy metals (lead, cadmium, nicke

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