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taining 1 mg/ ml of puromycin. A plasmid vector of BRCA1 splice variant, in which absence of exon 9 and 10 (designated as BRCA1 Delta(9,10)), was created by cloning the variant BRCA1 cDNA into the pcDNA3.1 expression vector using artificially engineered 59 HindIII and 39 XhoI sites. The BRCA1 cDNAs were contributed by Mien-Chie Hung (The University of Texas M. D. Anderson Cancer Center, Houston, T

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