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Phase II (hence, 100 repetitions, Gaussian noise). Some methods have parameters that could be varied: few permutations, tail approximation and gamma approximation use a certain number of permutations that varied in the simulations as J=40,60,100,200,300,500,1000,2000,5000. The negative binomial distribution uses a fixed upper limit on the number of permutations (set as J=50000) and a number of exc

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